Arthroscopic resection of ACL mucoid degeneration is effective for treating pain and flexion limitation, but at the expense of anterior laxity. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. This makes it difficult to relate the improvement of symptoms to ACL debridement. Outcome of Arthroscopic Treatment of Mucoid Degeneration of the Anterior Cruciate Ligament. No reconstruction was performed at the same time. 2013;15(1). It may lead to knee pain. reported the largest percentage of patients (27.5%) with a positive pivot test. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Reeducation. Knee Surg Sports Traumatol Arthrosc. The https:// ensures that you are connecting to the Postoperative ACL laxity is a common finding after ACL arthroscopic debridement, however, symptomatic instability is not. Hypothesis: Mucoid degeneration of ACL is a disease affecting ACL in which mucoid like substance (glycosaminoglycans) gets interspersed within the substance of ACL and as a result ACL gets thickened. (A) Bulging of, Fig. Mucoid degeneration (MD) of the anterior cruciate ligament (ACL) is a benign knee pathology, which is often indicated for surgical treatment if symptomatic. Four studies reported only postoperative scores, which were comparable to those in other studies. Seven of the nine studies reported using the Lachman test to check postoperative ACL laxity. Knee Surg Sports Traumatol Arthrosc. Epub 2011 Feb 18. On physical exam, the Lachman test for ACL instability is negative with an ACL ganglion. Sasaki R, Nagashima M, Takeshima K, Otani T, Okada Y, Aida S, Ishii K. J Int Med Res. Provided by the Springer Nature SharedIt content-sharing initiative. PubMedGoogle Scholar. Anatomopathology samples were collected in 18 cases. The origin of MDACL may be degenerative or traumatic. 1. An official website of the United States government. Generally, we know little about this condition. All rights reserved. as very low (04 points), low (58 points), good (912 points) or excellent (1316 points) [12]. The anterior cruciate ligament (ACL) is one of the more vital and more easily injured ligaments within our knee. Questions just answered: mucoid degeneration of acl physiotherapy. 2023 BioMed Central Ltd unless otherwise stated. The .gov means its official. Privacy Mucoid degeneration of the anterior cruciate ligament. Hsu CJ, Wang SC, Fong YC, Huang CY, Chiang IP, Hsu HC. Online ahead of print. I have persistent pain in the back of that knee that is exacerbated by walking and bending it. report that one patient had ACL reconstruction simultaneously after the ACL debridement. Methods: Clipboard, Search History, and several other advanced features are temporarily unavailable. 2010 Jun;96(4):400-6. doi: 10.1016/j.otsr.2010.02.008. 2007;15 (1): 73-86. and transmitted securely. Preoperative magnetic resonance imaging (MRI) scan. The presence of intraligamentous mucoid degeneration in the ACL is demonstrated as a source of knee pain without instability and partial ACL debridement did not preclude adequate knee stability. Anterior cruciate ligament ganglia and mucoid degeneration: coexistence and clinical correlation. and transmitted securely. The retrospective study by Kim et al. All nine studies included patients with symptomatic MDACL confirmed by MRI (Table3). ACL (anterior cruciate ligament) mucoid degeneration means the lesion of the ACL. The extracted data were heterogeneous in terms of outcome assessment. Careers. Answer (1 of 2): Most of the time mucoid degenrative changes in the ACL does not cause any problemonly if u have sign of ACL instability or the bending of the knee is reduced you may need a arthroscopic evaluation usually u may skip without ACL reconstruction but some of us will need AcL recons. . See this image and copyright information in PMC. Unauthorized use of these marks is strictly prohibited. All nine studies assessed the outcome of arthroscopic debridement of MDACL. Mucoid degeneration of ACL Justamom21 Feb 17, 2023 7:27 AM Among other conditions - osteoarthritis, osteopenia, spondylolisthesis- an MRI report showed "severe mucoid degeneration of the ACL" in my left knee. 2009 Jul;17(7):737-40. doi: 10.1007/s00167-008-0690-z. J Chin Med Assoc. Thirteen patients were treated with complete ACL resection for symptomatic MD of the ACL from 2006-2016. Mucoid degeneration of the anterior cruciate ligament (ACL) is a very rare cause of knee pain. FOIA Fourteen knees (48%) had limited flexion, on average 97 degrees. https://www.physio-pedia.com/index.php?title=Anterior_Cruciate_Ligament_(ACL)_Mucoid_Degeneration&oldid=253974, Difficulty in climbing stairs, cross-leg sitting, squatting, Primary condition- Osteoarthritis, degenerative menisci, meniscal tear, Impingement of the soft tissue in the vicinity. in 1999 [ 1 ]. https://doi.org/10.1007/s002560100336, Narvekar A, Gajjar S (2004) Mucoid degeneration of the anterior cruciate ligament. Mucinous material within the substance of ACL produces pain and limited motion in the knee. 8600 Rockville Pike Association between magnetic resonance imaging characteristics and pathological findings in entire posterior cruciate ligament with mucoid degeneration. The pathogenesis remains controversial. Correspondence to Its function is to stabilize the knee while bending and rotating; the ACL also keeps the knee from shifting out of place or moving anteriorly (toward the front) with pivoting activities. Sweed, T., Mussa, M., El-Bakoury, A. et al. Clin Orthop Surg 10(3):307314. 2022 Nov 24. doi: 10.1007/s00402-022-04659-z. MDACL is differentiated from synovial cysts of the anterior cruciate ligament (ACL) where, in MDACL, mucoid tissue intermingles within ACL fibres and is not contained within a cyst [3]. There was more than 20% loss to follow up in the study of Kim et al., while the three prospective studies had no loss to follow up [13, 14, 18]. 3. Level of evidence: 2011 Mar;25(3):262-5. Average postoperative differential laxity on the Telos device was 8.3 mm (5 to 13 mm). Later studies reported that changes consist of mucoid Results degeneration, neovascularisation, and tendon sheath hyper- Nineteen patients met the inclusion criteria and were inclu- trophy. eCollection 2013. [6], in 62% of patients (18 of 29) in the study of Lintz et al. sharing sensitive information, make sure youre on a federal Unlike meniscal tears and chondral defects, the mucoid degeneration of the anterior cruciate ligament (ACL) is a rare cause of knee pain and there have been no case reports of mucoid degeneration of both the ACL and the posterior cruciate ligament (PCL). Bethesda, MD 20894, Web Policies Bilateral Symptomatic Mucoid Degeneration of the Anterior Cruciate Ligament with Anterior Knee Pain but No Limited Knee Flexion. Careers. 2021 Oct 21;2021:5879121. doi: 10.1155/2021/5879121. Mucoid degeneration of the anterior cruciate ligament (MDACL) is a rare entity, first described by Kumar et al. Online ahead of print. Methods From January 2012 to August 2013, 32 knees (24 females and 8 males with left knee of 14 and 18 of right) were diagnosed with mucoid degeneration of the ACL and underwent arthroscopic treatment, all of whom with a mean age of 58.817.97 years (42-74 years). sharing sensitive information, make sure youre on a federal Orthopedics; anterior cruciate ligament; arthoscopy. (61years), which was the largest study and represented more than one third of the total patients included in this review. See this image and copyright information in PMC. Kim TH, Lee DH, Lee SH, Kim JM, Kim CW, Bin SI. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Cookies policy. An official website of the United States government. Several critical distinctions allow a confident diagnosis of an ACL ganglion cyst. What is Anterior Cruciate Ligament Mucoid Degeneration? We report a case of a patient with mucoid degeneration of the ACL, presenting with posterior knee pain and no history of a major knee trauma. Introduction: Mucoid degeneration of the anterior cruciate ligament (ACL) is a little-known entity. Knee Surg Sports Traumatol Arthrosc. The primary intervention was arthroscopic ACL debridement in eight studies; this was combined with notchplasty in cases of impingement with the lateral wall of the notch in five studies [6, 14, 16,17,18] (Table 3). -, McIntyre J, Moelleken S, Tirman P. Mucoid degeneration of the anterior cruciate ligament mistaken for ligamentous tears. https://doi.org/10.1007/s00167-011-1433-0, Article Introduction: Arch Orthop Trauma Surg. -Evaluated and planned treatment protocol in accordance with physician. Seventeen females (67%) and eight males (33%) were included in the final analysis. Pre-debridement arthroscopic view showing yellowish content in the anterior cruciate ligament. Postoperative follow-up included standard radiography and dynamic examination, measuring laxity with a Telos device. 2001;30(6):312315. When refering to evidence in academic writing, you should always try to reference the primary (original) source. 1. Mucoid degeneration (MD) of the anterior cruciate ligament (ACL) is a well-recognized pathology characterized by the degradation of collagen fibers and infiltration of a mucoidlike substance, [1,2 . Therefore, indications for ACL resection must be carefully selected. Signal intensity of the anteromedial bundle (AMB) or posterolateral bundle (PLB) graft standardized to the intensity of the PCL was defined as signal intensity ratio (SIR). For treatment of this, partial removing of bulky ACL is generally done, which causes weakness of the ACL. 2019 Jun;32(6):577-583. doi: 10.1055/s-0038-1660514. Histologically, there is a mucoid substance in connective tissue containing glycoproteins and mucoproteins [8]. Chudasama CH, Chudasama VC, Prabhakar MM. Mucoid degeneration of the anterior cruciate ligament is a rare pathological entity. Anterior cruciate ligament mucoid degeneration: selecting the best treatment option. In contrast to the tear, mucoid degeneration of the ACL characteristically does not cause knee instability [20, 21, 22]. -, Hensen JJ, Coerkamp EG, Bloem JL, De Schepper AM. The .gov means its official. J Knee Surg. A historical cohort of patients who underwent arthroscopic total or partial excision of the anterior cruciate ligament due to mucoid degeneration between 2011 and 2014 were reviewed. In this review, the mean age of patients ranged from 31 to 78years; mean age was highest in the study of Kim et al. What is myxoid degeneration treatment? An official website of the United States government. Conclusions Our study provides further evidence that arthroscopic total or partial excision of anterior cruciate ligament is a safe and effective treatment for mucoid degeneration of the anterior . Epub 2010 May 8. Disclaimer. Postoperative pain relief ranged from 53.8 to 95%. 2011. "Traumatic theory - post injury, ACL fibroblasts secrete glycosaminoglycans, the mucin substance within the ACL. Mucoid degeneration (MD) of the anterior cruciate ligament (ACL) is a benign knee pathology, which is often indicated for surgical treatment if symptomatic. Mucoid degeneration of the ACL is suspected when an apparently thickened and ill-defined ligament with increased signal intensity on all sequences in MRI is identified in a patient with physically intact ligament and no obvious trauma history. 2007;245 (3): 916-7. Epub 2010 May 8. to 44% in the study of Cha et al. Exclusion criteria were (1) case reports, literature reviews and conference abstracts and (2) studies written in languages other than English. https://doi.org/10.1046/j.1445-2197.2003.02748.x, Ekhtiari S, Horner NS, Bedi A, Ayeni OR, Khan M. The learning curve for the Latarjet procedure: a systematic review. The mean age at the time of surgery was 57 years (range, 31 to 78 years). The knee is a complex synovial joint that can be affected by a range of pathologies: Please Note: You can also scroll through stacks with your mouse wheel or the keyboard arrow keys. Second, methodological quality assessment showed that three studies had low methodological quality. Method. Arthroscopic debridement of the mucoid degeneration of the ACL was safe and effective in the patient. Discussion: 2006;69(9):44952. 1. 2004;182(5):12831287. Typically patients present with knee pain or restricted movement, although often other potential causes for the patient's symptoms are found. Arthroscopic debridement of the ACL was the intervention in eight studies, whereas Morice et al. Mucoid degeneration, is the irreversible degeneration of the tissue with the infiltration of mucin(glycosaminoglycans) within the fibers[1][2]. 2022 Mar;14(1):76-89. doi: 10.4055/cios20163. 5. Our study provides further evidence that arthroscopic total or partial excision of anterior cruciate ligament is a safe and effective treatment for mucoid degeneration of the anterior cruciate ligament, improving patient satisfaction and function without causing clinical instability in daily activities. HHS Vulnerability Disclosure, Help sharing sensitive information, make sure youre on a federal Preoperative magnetic resonance imaging (MRI), Fig. What Is Mucoid Degeneration of the ACL? Characteristic: "celery stalk" appearance. Bone and joint imaging. Quadriceps and hamstring weakness are common features of people with symptomatic degenerative meniscal tears Surgery may address the structural injury, but . Epub 2018 Jun 13. mucoid degeneration of acl mri. This site needs JavaScript to work properly. Presentation Patients usually present with nonspecific posterior knee pain with restriction of flexion. PubMed Central Unauthorized use of these marks is strictly prohibited. ACL ganglion cyst at arthroscopy may appear as a cystic mass with . Management of mucoid degeneration of the anterior cruciate ligament: a systematic review, https://doi.org/10.1186/s43019-021-00110-6, https://doi.org/10.1302/0301-620X.81B2.0810304, https://doi.org/10.1007/s00167-011-1433-0, https://doi.org/10.2214/ajr.182.5.1821283, https://doi.org/10.1007/s00167-012-1991-9, https://doi.org/10.1016/j.arthro.2003.11.030, https://doi.org/10.1016/j.jclinepi.2009.06.005, http://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42018087782, https://doi.org/10.1046/j.1445-2197.2003.02748.x, http://journals.sagepub.com/doi/10.1177/2325967118786930, http://www.ijcrar.com/abstractview.php?ID=228&vol=4-11-2016&SNo=3, https://doi.org/10.1016/j.arthro.2008.02.004, https://doi.org/10.1016/j.jajs.2015.12.001, https://doi.org/10.4055/cios.2018.10.3.307, http://creativecommons.org/licenses/by/4.0/, http://creativecommons.org/publicdomain/zero/1.0/. Quality was assessed using the Methodological Index for Non-Randomized Studies (MINORS) criteria. The site is secure. A posterior approach will allow for the detection of changes by probing the ligament and mucoid material can be expressed. Epub 2008 Apr 18. All patients (100%, n=11) reported a good to very good surgery satisfaction. Management of mucoid degeneration of the anterior cruciate ligament: a systematic review. Morice et al. The main MRI finding of ACL mucoid degeneration is a celery stalk appearance [26, 27]. Its prevalence in magnetic resonance imaging (MRI) is 1.8 to 5.3%, but not all lesions are symptomatic. Clipboard, Search History, and several other advanced features are temporarily unavailable. They respond well to a judicious arthroscopic release of the ACL with notchplasty. Mucoid degeneration of the anterior cruciate ligament: a case report. Noninfiltrating synovial cysts of the ACL were excluded. The clinical presentation is one of posterior pain with limited flexion. reported on the co-existence of mucoid degeneration and ganglia of the ACL. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. Arthroscopy 24(6):642649. https://doi.org/10.4055/cios.2018.10.3.307, University Hospitals of Derby and Burton, Uttoxeter Rd, Derby, DE22 3NE, UK, Trauma and Orthopaedic Speciality Trainee, West Midlands Deanery, Birmingham Rotation, Birmingham, UK, University Hospitals Plymouth NHS Trust, Plymouth, UK, University of Alexandria, Alexandria, Egypt, University Hospital Coventry and Warwickshire, Clifford Bridge Road, Walsgrave, Coventry, CV2 2DX, UK, You can also search for this author in 42 Mucoid degeneration of the anterior cruciate ligament with erosion of the lateral femoral condyle P. Melloni, R. Valls, M. Yuguero, A. Saez Medicine Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. Sometimes, it is mislead as ACL tear on MRI findings, hence requires probing and histopathology for definitive diagnosis. eCollection 2022 May-Jun. Hamdaoui and others published Le signe de la branche de cleri | Find, read and cite all the research you need on ResearchGate This bicentric, retrospective cohort study with an average follow-up of 6years involved 27 patients (29 knees) presenting with symptomatic ACL mucoid degeneration validated by magnetic resonance imaging (MRI). Due to the lack of specific symptoms and signs, its diagnosis is often delayed or even misdiagnosed in clinical practice [ [1] , [2] ]. https://doi.org/10.1016/j.arthro.2003.11.030, Moher D, Liberati A, Tetzlaff J, Altman DG (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Data extracted included mean age and gender of the patients, duration of follow up, associated chondral and meniscal lesions, interventions and outcomes. Bookshelf Careers. Mumbai, Maharashtra, India. A June 2018 MRI of the cervical spine found multilevel degenerative changes of the cervical spine, most pronounced at 6-7 and small disc herniations at 5-6 and C4-5, with slight interval progression at 5-6. . Individuals were included in the study if they had had complete MRIs of the affected knee at baseline and at 4-year follow-up, had thigh MRIs at baseline and had no additional surgery in the meantime. An anterior cruciate ligament (ACL) mucoid degeneration, along with tears and anterior cruciate ligament ganglion cysts, is a relatively common cause of increased signal within the. PMC http://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42018087782. Federal government websites often end in .gov or .mil. First, our literature search revealed a heterogeneous group of studies dominated by case reports and case series, with no randomised controlled trials. Sweed T, Mussa M, El-Bakoury A, Geutjens G, Metcalfe A. Knee Surg Relat Res. The .gov means its official. Manage cookies/Do not sell my data we use in the preference centre. Postoperative ACL laxity is common after arthroscopic ACL debridement, however, symptomatic instability is not. Conclusions: Mucoid degeneration of the ACL is a clinical condition afflicting active middle-aged people without a single significant traumatic episode with a specific MRI picture. Arthroscopic treatment may include ACL resection, which raises the questions about the harmlessness of this procedure and the risk of anterior instability. A September 2018 MRI of the left knee showed anterior cruciate ligament and mucoid degeneration with intra cruciate ganglion . Study record managers: refer to the Data Element Definitions if submitting registration or results information.. Search for terms The site is secure. Mucoid degeneration of the anterior cruciate ligament (MD-ACL) was first described in the literature in 1999.1 Since then, MD-ACL has been recognized as a pathology present on between 0.7% and 5.3% of magnetic resonance images performed for knee pain.2 MD-ACL is thought to be part of a spectrum of ACL disease that can range from ganglion cysts to MD.3 MD-ACL can either be primary (idiopathic . -Provided skilled hands on in post-op rehabilitation to various population including Head and neck cancers, Lymph edema management, Bone cancers. AJR Am J Roentgenol. 2011 Aug;19(8):1326-33. doi: 10.1007/s00167-011-1433-0. Epidemiology The likelihood of mucoid change within ligaments and tendons increases with age 1. Clin Orthop Surg. Download Citation | On Feb 1, 2023, O.R. Google Scholar, Cha JR, Lee CC, Cho SD, Youm YS, Jung KH (2013) Symptomatic mucoid degeneration of the anterior cruciate ligament. Resnick D, Kransdorf MJ. TS designed the project, literature search and wrote the manuscript. Radiologic findings associated with mucoid degeneration of the anterior cruciate ligament. Loss to follow up was not mentioned in the other five studies [3, 6, 15, 17, 19]. Dietary management and various treatments Scanning and diagnostic . However, the authors did not report whether there were any other patients with symptomatic instability. Would you like email updates of new search results? Coronal proton density-weighted magnetic resonance, Coronal proton density-weighted magnetic resonance imaging shows a thickening of the anterior cruciate, Sagittal proton density-weighted magnetic resonance, Sagittal proton density-weighted magnetic resonance image shows ill-defined anterior cruciate ligament with increased, Coronal T2 weighted fat suppressed fast spin echo image showed complex anterior cruciate, Pre-debridement arthroscopic view showing yellowish. Correlations between degree of knee instability and SIR were assessed for each bundle, each time point, and each sequence. 2013 Oct;99(6):693-7. doi: 10.1016/j.otsr.2013.04.010. 2010 Jun 1;96(4):400-6. Anterior Cruciate Ligament, is an important structure of the knee joint. ACL debridement was partial in all studies except for those by Lintz et al. Lintz F, Pujol N, Boisrenoult P, Bargoin K, Beaufils P, Dejour D. Anterior cruciate ligament mucoid degeneration: a review of the literature and management guidelines. maude adverse event report: genzyme biosurgery (ridgefield) synvisc one intra-articular hyaluronic acid The prevalence of mucoid degeneration of the ACL has been reported to be 0.43% [ 5 ]. Lintz F, Pujol N, Dejour D, Boisrenoult P, Beaufils P. Orthop Traumatol Surg Res. Open Grey database was searched for grey literature using the same keywords. Kumar A, Bickerstaff DR, Grimwood JS, Suvarna SK (1999) Mucoid cystic degeneration of the cruciate ligament.