May also be prescribed off label for Esophageal Spasm. [2] It can be used both to treat and to prevent heart-related chest pain; however, it is generally less preferred than beta blockers or calcium channel blockers. Some brands of isosorbide mononitrate tablets should be taken two or three times a day. Synthroid (levothyroxine) Tylenol (acetaminophen) Vitamin B12 (cyanocobalamin) Vitamin C (ascorbic acid) Vitamin D3 (cholecalciferol) Isosorbide mononitrate disease interactions There are 7 disease interactions with isosorbide mononitrate which include: AMI anemia hemodialysis hypotension intracranial pressure hypertrophic cardiomyopathy glaucoma HHS Vulnerability Disclosure, Help Check with your doctor immediately if any of the following side effects occur: burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, fast, slow, irregular, pounding, or racing heartbeat or pulse, itching, pain, redness, or swelling on the leg, numbness or tingling in the hands, feet, or lips, pain or discomfort in the arms, jaw, back, or neck, pain, tension, and weakness upon walking that subsides during periods of rest, shakiness in the legs, arms, hands, or feet, swelling of the face, fingers, feet, or lower legs, trembling or shaking of the hands or feet, vomiting of blood or material that looks like coffee grounds, Bluish-colored lips, fingernails, or palms. If you are having an operation or dental treatment, please remember to tell the person carrying out the treatment which medicines you are taking. Many common herbal supplements interact with common heart medicines. Swallow the extended-release tablets or capsules whole; do not crush, chew, or divide them. Some of these medicine interactions can be risky. Dated August 2017. Pregnancy:Data on the use of isosorbide mononitrate during pregnancy are insufficient to be able to assess the possible harmful effect. Alcohol or marijuana (cannabis) can make you more dizzy. Classes: Nitrates, Angina Print Dosing & Uses AdultPediatricGeriatric Dosage Forms & Strengths tablet 10mg 20mg. Isosorbide mononitrate works in two ways. You could also spray your face with cool water or sip non-alcoholic cold or iced drinks. In case of overdose, call the poison control helpline at 1-800-222-1222. Do not take more or less of it or take it more often than prescribed by your doctor. There are 195 drugs known to interact with Is isosorbide mononitrate (Monoket) the same as nitroglycerin (Nitrostat)? I took this for 4 days, and my headaches were unbearable. If you forget to take a dose, take it as soon as you remember. It took me a few weeks to adapt to it, but the effect on preventing chest pain was dramatic. View interaction reports for isosorbide mononitrate and the medicines listed below. This is not a complete list of possible side effects. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. We comply with the HONcode standard for trustworthy health information. Fish Oil (omega-3 polyunsaturated fatty acids), Email this report to a friend, doctor, or patient, isosorbide mononitrate consumer information. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Please enable it to take advantage of the complete set of features! 8600 Rockville Pike Evening primrose. Isosorbide mononitrate tablets and capsules are not suitable to take to treat the pain of an angina attack. Methods: Integrative medicine (complementary and alternative medicine). Natural Medicines. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). Keep this medication in the container it came in, tightly closed, and out of reach of children. Minimally clinically significant. 7.6 out of 10 from a total of Let your provider know if they are excessive. The information on this page is written and peer reviewed by qualified clinicians. While both isosorbide mononitrate (Monoket) and nitroglycerin (Nitrostat) are both nitrate vasodilators, they are not the same medication. Cardizem may also be used for purposes not listed in this medication guide. Headache and weakness of left side (both arm and leg) may suggest a brain pathology. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Less commonAbnormal heart soundabsence of or decrease in body movementarm, back, or jaw painblack, tarry stoolsbladder painbleeding after defecationbleeding gumsblood in the urine or stoolsblurred visionbody aches or painburning while urinatingburning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelingschest pain or discomfortchest tightness or heavinesschillscold sweatscoldsconfusionconvulsionscough or hoarsenessdecreased urinediarrheadifficult or labored breathingdifficult, burning, or painful urinationdilated neck veinsdizzinessdizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting positiondry mouthear congestionextra heartbeatsfaintingfast, slow, irregular, pounding, or racing heartbeat or pulsefever or chillsflu-like symptomsfrequent urge to urinatefrequent urinationgeneral feeling of discomfort or illnessheadacheheadache, severe and throbbingheart murmurincreased need to urinateincreased sweatingincreased thirstincreased volume of pale, dilute urineirregular breathingitching, pain, redness, or swelling on the legjoint pain, stiffness, or swellinglightheadednessloss of appetiteloss of voicelower back, side, or stomach painmuscle aches and painsmuscle crampsnasal congestionnausea or vomitingnervousnessnumbness or tingling in the hands, feet, or lipspain or discomfort in the arms, jaw, back, or neckpain, tension, and weakness upon walking that subsides during periods of restpartial or slight paralysispassing urine more oftenpinpoint red or purple spots on the skinpounding in the earsrunny noseshakiness in the legs, arms, hands, or feetshiveringsneezingsore on the legsore throatsudden decrease in the amount of urinesweatingswellingswelling of the face, fingers, feet, or lower legstightness in the chesttrembling or shaking of the hands or feettrouble sleepingtroubled breathinguncomfortable swelling around the anusunusual bleeding or bruisingunusual tiredness or weaknessvomiting of blood or material that looks like coffee groundsweaknessweight gainRareBluish-colored lips, fingernails, or palmsdark urinepale skinrapid heart rateGet emergency help immediately if any of the following symptoms of overdose occur:Symptoms of overdoseBlurred or loss of visionbulging soft spot on the head of an infantchange in consciousnesschange in the ability to see colors, especially blue or yellowcold, clammy skindisturbed color perceptiondouble visionfeeling of constant movement of self or surroundingshalos around lightsheadache, severe and throbbingloss of consciousnessnight blindnessoverbright appearance of lightsparalysissensation of spinningtunnel visionSome side effects may occur that usually do not need medical attention. Properly discard this product when it is expired or no longer needed. Valerian: A safe and effective herbal sleep aid? Call your doctor for medical advice about side effects. Registered in England and Wales. Isosorbide mononitrate (Monoket) is a nitrate vasodilator. The body tends to develop a tolerance (decreased sensitivity) to ISMN when it is used continuously over 24 hours. It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. Advertising revenue supports our not-for-profit mission. Always consult your healthcare provider. Don't drink alcohol while taking isosorbide mononitrate (Monoket). Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. What special dietary instructions should I follow? Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. Overview of herbal medicines and dietary supplements. What side effects can this medication cause? It works and leaves the body quickly, so it needs to be taken twice a day. Diabetes treatment: Can cinnamon lower blood sugar? When used regularly on a long-term basis, this helps prevent angina attacks from occurring. This content does not have an English version. Limited data from animal studies indicate no adverse effects on the pregnancy or the unborn child. URL of this page: https://medlineplus.gov/druginfo/meds/a682348.html. Nitrates in the management of acute coronary syndrome. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Enter other medications to view a detailed report. Isosorbide mononitrate (Monoket) is available as a generic medication and may be significantly cheaper compared to the brand version. Never take more than the prescribed dose. Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Also, it is not intended to be taken just before physical activities (such as exercise or sexual intercourse) to prevent chest pain. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Please see a good cardiologist, get admitted, get checked thoroughly. Side effects : headache, mild dizziness This is a condition where the heart does not beat as efficiently as it should. This product is available in the following dosage forms: There is a problem with This activity describes the indications, action, and contraindications for isosorbide as a valuable agent in treating angina pectoris due to coronary artery disease, heart failure with reduced . May also be prescribed off label for Esophageal Spasm. it is a safe and effective alternative; the choice between beta blockers and calcium channel blockers depends . Melanoma is one of the most dangerous forms of skin cancer which develops in the skin cells that produce melanin ( the pigment that gives your skin its color). Sept. 26, 2022. If you have any problems with the way your liver works, or any problems with the way your kidneys work. In: Textbook of Natural Medicine. There are 7 disease interactions with isosorbide mononitrate which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Cao HY, Wu HD, Song ZK, Tang ML, Yang S, Liu Y, Qin L. Pan Afr Med J. Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets; Merus Labs Luxco S.a.R.L, The electronic Medicines Compendium. Background: Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. Should I avoid certain foods while taking Isosorbide Mononitrate? Available for Android and iOS devices. Laboratory and/or medical tests (such as blood pressure) should be performed periodically to monitor your progress or check for side effects. Use of herbal products and potential interactions in patients with cardiovascular diseases. When used regularly on a long-term basis, this helps prevent angina attacks from occurring. Take isosorbide exactly as directed. Isosorbide mononitrate: isosorbide mononitrate. Am J Ther. https://naturalmedicines.therapeuticresearch.com. 2005 - 2023 WebMD LLC. Isosorbide mononitrate (Monoket) is not a medication you take if you think you are having a heart attack. To view a report comparing 3 (or more) medications, please sign in or create an account. Trapidil is as effective as isosorbide-dinitrate for treating stable angina pectoris: a multinational, multicenter, double-blind, randomized study. It also relaxes and widens blood vessels in your heart (coronary arteries) which increases the flow of blood to your heart muscle. Imdur (isosorbide mononitrate) Extended Release and Isordil (isosorbide dinitrate) are vasodilators indicated for the prevention of angina pectoris due to coronary artery disease.. Side effects of Imdur and Isordil that are similar include headache and dizziness.. Side effects of Isordil that are different from Imdur include weakness and skin changes such as redness, tingling, or warmth. It is not intended as medical advice for individual conditions or treatment. You can take your doses either before or after meals. 2021 May 11;39:28. doi: 10.11604/pamj.2021.39.28.22180. Isosorbide mononitrate. My blood pressure, cholesterol and pulse are all normal and I have no chest pains, shortness of breath or other heart problem symptoms. Do not drink alcohol while taking View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. Does Isosorbide Mononitrate interact with other drugs you are taking? With any medication, there are risks and benefits. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. For these reasons, before you start taking isosorbide mononitrate it is important that your doctor knows: Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. If you buy any medicines, please check with a pharmacist that they are suitable for you to take with isosorbide mononitrate. St. John's wort. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Patient is a UK registered trade mark. Yet significantly fewer patients had headache on low dosage than on high dosage (45 vs 57, P < 0.02). Methods: In a randomized, double-blind, crossover study, 89 patients with stable angina pectoris were studied to compare two different dosage strategies of isosorbide-5-mononitrate (5-ISMN). Commonly reported side effects include: See also: isosorbide mononitrate side effects in more detail. These relax smooth muscle within the blood vessels, widening them and making it easier for blood and oxygen to reach the heart Calcium antagonists (eg, diltiazem, nifedipine, nimodipine, verapamil). Mayo Clinic; 2021. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. This information is aggregated and used to produce personalized reports that patients can reference. What are the side effects of Isosorbide Mononitrate ? Isosorbide tablets are also used with other medications to treat heart failure. Unauthorized use of these marks is strictly prohibited. Of the total drug interactions, Continue to take isosorbide even if you feel well. Good at preventing chest pain caused by heart disease, Available as a generic version, making it less expensive, Long-acting version only needs to be taken once daily, Short-acting tablets have to be taken on a very specific schedule for the medication to work best. To avoid this problem, get up slowly, resting your feet on the floor for a few minutes before standing up. Receive price alerts, news, and other messages from GoodRx about isosorbide mononitrate (Monoket) and other healthcare topics and relevant savings offers. Coenzyme Q-10 Natural Medicines. Never give it to other people even if their condition appears to be the same as yours. AHFS Patient Medication Information. Make sure laboratory personnel and all your doctors know you use this drug. The .gov means its official. Taking erectile dysfunction medications or drinking alcohol while taking isosorbide mononitrate (Monoket) can cause your blood pressure to get dangerously low, which can be life-threatening. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Alternative cancer treatments: 11 options to consider. Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.Isosorbide mononitrate is used to prevent angina attacks (chest pain). (2) One in 3 patients never experienced headache from the given dosages. Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Less commonAcid or sour stomachanxietyback painbelchingblemishes on the skinbloatedbreast painburning feeling in the chest or stomachburning, dry, or itching eyeschange in color visionchanges in visioncold sweatscongestionconstipationcontinuing ringing or buzzing or other unexplained noise in the earscough producing mucusdecreased interest in sexual intercoursedifficulty seeing at nightdifficulty with movingdischarge, excessive tearingdouble visiondrooping upper eyelidsdull ache or feeling of pressure or heaviness in the legsearacheexcess air or gas in the stomach or intestinesfeeling of constant movement of self or surroundingsfeeling of warmthfeeling unusually coldfrequent urge to defecatefrozen shoulderfull feelinghearing lossheartburnhyperventilationinability to have or keep an erectionincreased appetiteincreased sensitivity of the eyes to sunlightincreased sputumindigestionirritabilityitching skin near damaged veinslack or loss of strengthloss in sexual ability, desire, drive, or performancemuscle or bone painmuscle stiffness or weaknessnightmaresnoisy breathingpain or tenderness around the eyes and cheekbonespassing gaspimplespoor concentrationrashredness of the face, neck, arms, and occasionally, upper chestredness, pain, swelling of the eye, eyelid, or inner lining of the eyelidredness, swelling, or soreness of the tonguerestlessnessseeing doublesensation of spinningsleepiness or unusual drowsinesssmall clicking, bubbling, or rattling sounds in the lung when listening with a stethoscopesmall lumps under the skinsore mouth or tonguestiff neckstomach bloating, burning, cramping, or painstomach discomfort or upsetstraining while passing stoolstuffy nosesudden sweatingswollen feet and anklestender, swollen glands in the necktenderness in the stomach areaterrifying dreams causing sleep disturbancestooth disordertrouble swallowinguncontrolled twisting movements of the neckvoice changesweight losswhite patches in the mouth, tongue, or throatOther side effects not listed may also occur in some patients. If you are having difficulty accessing this website, please call or email us at (855) 268-2822 or ada@goodrx.com so that we can provide you with the services you require through alternative means. Isosorbide mononitrate helps to prevent angina chest pain from developing. Accessed Sept. 7, 2022. What special precautions should I follow? US residents can call their local poison control center at 1-800-222-1222. Truven Health and GoodRx make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Journal of the American College of Cardiology. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. So get a ct scan brain apart from cardiology workup. If you have any questions about this medicine ask your pharmacist. Highly clinically significant. Isosorbide mononitrate should not be used in patients with severe anaemia, severe hypotension, closed angle glaucoma or severe hypovolaemia.Isosorbide mononitrate may give rise to postural hypotension and syncope in some patients. Accessed Sept. 7, 2022. Stopping isosorbide mononitrate (Monoket) suddenly can cause you to have a worsening of your chest pain. This chest pain can feel more intense or painful than it was before you began taking isosorbide mononitrate (Monoket). [2] 88 ratings on Drugs.com. Journals of the American College of Cardiology. Accessed Sept. 7, 2022. Yes, it's good for health but don't take it excesse in amount, use once daily for 1 month then stop it or take once a weekly. This site complies with the HONcode standard for trustworthy health information: verify here. https://naturalmedicines.therapeuticresearch.com. Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Therefore, oral nitrates should not be used by patients who are sensitive to the effects of hypotension, such as those with pre-existing hypotension, shock, vascular collapse or significant cerebrovascular disease, significant anaemia or hypothyroidism. Patient does not provide medical advice, diagnosis or treatment. Let your provider know if you are using any medications for erectile dysfunction before you start taking isosorbide mononitrate (Monoket). The effects of this exposure on a nursing infant are unknown. from the best health experts in the business. Canada residents can call a provincial poison control center. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Patients were randomized to either 60 mg 5-ISMN once daily (od) for two weeks or . It does not have such side effects. However, you should not flush this medication down the toilet. Isosorbide mononitrate, sold under many brand names, is a medication used for heart-related chest pain ( angina ), heart failure and esophageal spasms. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Your provider might temporarily have you stop isosorbide mononitrate (Monoket) if this happens. Isosorbide mononitrate (Monoket) can cause headaches, dizziness, or lightheadedness. Botanical medicine A modern perspective. prevention of anginal chest pain associated with coronary artery disease, prevent bleeding varicose vein in the esophagus. Isosorbide dinitrate (Isordil) is available as both a short-acting tablet and long-acting capsule. It is also important information to carry with you in case of emergencies. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Lifestyle changes such as dietary changes, exercise, and not smoking may help this drug work better. Ask your doctor before using aspirin together with alcohol. Ask your pharmacist any questions you have about refilling your prescription. The herb licorice may lower warfarin levels and can add to digoxin's effects. Zhonghua Yi Xue Za Zhi (Taipei). See also: aspirin side effects in more detail. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. ** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. include protected health information. Are you looking for information on isosorbide dinitrate (Isordil) instead? For instance, many herbal supplements that are used often interact with the blood thinner warfarin (Jantoven). Theyre fast, easy-to-use and free! These products are provided 'AS IS' and 'as available' for use, without warranties of any kind, either express or implied. Below is the list of medicines, which contains Isosorbide Mononitrate as ingredient. GoodRx works to make its website accessible to all, including those with disabilities. If you miss a dose, take it as soon as you remember. Includes Isosorbide Mononitrate indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more. Now, youll enjoy a streamlined experience created specifically for healthcare providers. isosorbide mononitrate (Rx) Brand and Other Names: Imdur, Monoket, more. Otherwise, call a poison control center right away. Some people feel dizzy or fall when changing positions, such as going from sitting to standing. Isosorbide is in a class of medications called vasodilators. Thirty percent of the patients never experienced headache from the given dosages. Some conditions may become worse when the drug is suddenly stopped. Almost 70% of older adults use them. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. Talk to your provider if you notice your chest pain starts to get worse. Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). This document does not contain all possible drug interactions. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. This is so your doctor can check on your progress.
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